Concerning Agglutinins for Treponema Pallidum
نویسنده
چکیده
1. There is no demonstrable amount of agglutinin for Treponema pallidum (Noguchi) in normal human and normal rabbit serum in dilutions as low as 1:20. 2. Agglutinins for Treponema pallidum are readily produced in young rabbits by the administration of pure cultures of living spirochetes. 3. There is no appreciable amount of agglutinin for Treponema pallidum culture used in the sera of secondary and tertiary syphilis or in the cerebrospinal fluid of tertiary syphilis in dilutions of 1:20 to 1:640.
منابع مشابه
Antibody Formation against Treponema Pallidum—agglutination
It has been shown by our experiments that the serum of rabbits treated with emulsions of Treponema pallidum contains agglutinating substances. Normal rabbit serum also possesses agglutinating power for this organism, but, as in the case of normal bacterial agglutinins, to an extent very much inferior to that possessed by the sera of immunized animals. Normal human sera will agglutinate similar ...
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The results observed with this strain of Treponema pallidum may be stated as follows: 1. Normal human serum did not agglutinate this culture of Treponema pallidum in dilutions of 1:5 or higher; equal parts of treponema culture and normal serum (dilution 1:2) resulted in agglutination in about 50 per cent of the sera. With the strain of Treponema pallidum used in this study specific agglutinatio...
متن کاملSpecific Agglutination of Treponema Pallidum by Sera from Rabbits and Human Beings with Treponemal Infections
A method has been described for the preparation of Treponema pallidum suspensions that are suitable for specific agglutination studies and can be stored at 4 degrees C. for months without loss of agglutinability. Such suspensions have been shown to react with two distinct antibodies in the serum of syphilitic animals and man: Wassermann antibody and a specific treponeme agglutinin. It has been ...
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BACKGROUND AND PURPOSE Widal test is frequently applied for the detection of Salmonella agglutinins to diagnose Salmonella enterica serotype Typhi infection. There are however a number of controversies challenging the diagnostic utility of this test. This study was performed to determine the prevalence of Salmonella agglutinins in patients with other febrile illnesses and healthy blood donors. ...
متن کاملDetection of biological false positive syphilis serum reactions.
a lipoidal fraction, which, acting as a hapten, combines with the protein of the treponema and stimulates thl? production of antibodies (reagin) which can be measured by the so-called reagin tests. The first treponemal test using T. pallidum was introduced by Nelson and Mayer' in 1949 when they described the Treponema pallidum immobilisation test (TPI). In this test the serum of patients showin...
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ورودعنوان ژورنال:
- The Journal of Experimental Medicine
دوره 18 شماره
صفحات -
تاریخ انتشار 2003